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KMID : 0382619930130010459
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Hanyang Journal of Medicine
1993 Volume.13 No. 1 p.459 ~ p.468
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The fate of Chost cell in Trabecular Meshwork in Experimental Ghost Cell Hyphema
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Abstract
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This study was performed to confirm whether ghost cell in the anterior chamber could block the outflow pathway to lead the increased in the intraocular pressure. Autologous ghost cell was injected into the anterior chamber to observe the facte of
the
ghost cell in 6 pigmented rabbits within normotensive ocular pressure. The fresh blood from the 6 pigmented rabbits was aspirated to make ghost cell, which was formed in the incubator under the two weeks- incubation. The eyeball was enucleated on
3
days, 7 days and 14 days after injection of ghost cell into the anterior chamber respectively to observe the trabecular meshork under transmission electron microscopy.
Ghost cells an red cellular debris are observed within the cytoplasm of the macropphage and endothelial cells of the trabecular meshwork. The nuclear membrane of the trabecular endothelial cell was also markedly indented to indicated the
increased
activity of the endothelial cell.
These findings suggest that ghost cells and red cellular debris may be eliminated through the processes of the phagocytosis and digestion by the trabecul;ar endothelial cell as the biologic filter. Ghost cell within the trabecular meshwork may be
a
minor role in the elevation of the intraocular pressure.
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